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Purchase Gummies Online Perth Medicated Edibles Online Queensland Buy Weed Online Australia Get Weed Online Brisbane Smoking or vaporising cannabis produces a rapid and transient peak in blood and oral fluid THC concentrations. When taken orally, cannabis is absorbed more slowly through the gastrointestinal tract, producing far lower blood THC concentrations. THC is highly lipophilic and is readily absorbed into fatty tissue, from where it can slowly re-enter the bloodstream days or even weeks following cannabis consumption. Blood THC concentrations are therefore not necessarily indicative of recent cannabis consumption or the amount of cannabis consumed. The mere presence of THC in blood or oral fluid THC does not reliably predict impairment, although current mobile drug testing methods and associated laws rely entirely on this
In contrast, CBD is non-intoxicating and has current regulatory approval in Australia for certain rare forms of childhood epilepsy as a 100 mg/mL oral formulation (Epidyolex). There is also emerging evidence of CBD efficacy in treating anxiety, psychosis, chronic pain and neurological disorders.5–7 There is some limited evidence that CBD can counteract negative THC-related side effects such as anxiety and paranoia.8,9 There is a rapidly growing worldwide market for CBD ‘wellness’ products. Such products typically contain very low CBD doses (eg 5–50 mg) that are of uncertain therapeutic value.10,11
With the exception of the oral THC/CBD spray nabiximols (Sativex) and the CBD oil Epidyolex, medical cannabis products in Australia are all unregistered medicines as they have not been formally assessed by the TGA for safety, quality or efficacy. These are predominantly oral preparations, oromucosal sprays and capsules; they can be THC dominant, CBD dominant or contain a specific mix of THC and CBD.12 Cannabis plant material is also available but less commonly prescribed. Therapeutic THC doses are typically in the range of 5–20 mg, while CBD doses tend to be higher (eg 50–1500 mg). Buy Weed Online Australia
The TGA has recently announced that CBD products meeting certain specifications will be down-scheduled from Schedule 4 to Schedule 3 and therefore available in pharmacies as over-the-counter products. Such products will be limited to a maximum dose of 150 mg/day and for oral or sublingual administration. At present, there are no CBD products that have obtained regulatory approval under Schedule 3,13 although there likely will be within the next 12–24 months once companies have had products approved by the TGA for registration on the Australian Register of Therapeutic Goods. Medicated Edibles Online Queensland
Legislative changes
The Victorian government is currently considering legislation that would allow patients using medical cannabis to legally drive with THC in their systems as long as they are not impaired.35 This would bring cannabis and driving laws insofar as they apply to patients into line with current laws for other drugs known to impair driving, such as opioids and benzodiazepines. These changes would not extend to the large number of patients self-medicating with illicit cannabis products.36
THC detection times
THC is typically detectable in oral fluid for 4–6 hours after smoking or vaporising cannabis, although this is highly variable across individuals and depends on factors such as salivary composition, flow rate, time since eating and frequency of THC use. In very heavy cannabis users, THC may be detectable in oral fluid for up to three days following abstinence.37,38 In blood, THC is commonly detectable for up to seven days,39,40 and in extreme cases, for up to 30 days41 following cessation of use. In urine, THC may be detectable for up to 24 days, depending on the sensitivity of the test.42 The secondary, inactive metabolite of THC, 11-nor-9-carboxy-THC (THC-COOH), which is very commonly used in workplace drug tests, can be detected for up to three months in very heavy cannabis users. Purchase Gummies Online Perth
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